Immune and Anti-oxidant Functions of Ethanol Extracts of Scutellaria baicalensis in Mice Bearing U14 Cervical Cancer

Scutellaria baicalensis Georgi (SBG) is a traditional Chinese herbal medicine used to clear fever, release fire, neutralize poison, stop bleeding and prevent miscarriage in the form of decoction or extracts. It is confirmed that the active components of the root of SBG are flavonoids which have anti-inflammatory and anti-allergic effects, antioxidant, anti-thrombotic and vasoprotective properties (Su et al., 2008; Kesarkar et al., 2009). Previous studies have also reported that ethanol extract of SBG could prevent oxidative damage and show anti-oxidation, antiinflammation and induction cell apoptosis effects (Jeong et al., 2011; Lu et al., 2011; Lin et al., 2013). However, the effects of SBG on immune and anti-oxidant function of mice bearing tumors, especially cervical cancer, are relatively unknown. Cervical cancer which is mainly infected by high risk human papilloma virus (HR-HPV, HPV16 and HPV 18 were the commonest genotypes) is one of the most common cancer affecting women worldwide (Bosch et al., 1995; Wang et al., 2013). In many developing countries,